TRexBio Q3 2026 Financial Results and Pipeline Updates

Biotechnology
Biotechnology
Earnings
Earnings
IPO:
Oct 09, 2026
Industry:
BIOLOGICAL PRODUCTS, (NO DISGNOSTIC SUBSTANCES)

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TRexBio Reports Third Quarter 2026 Financial Results and Recent Business Highlights

SOUTH SAN FRANCISCO, Calif., Nov. 13, 2026 -- TRexBio, Inc. (Nasdaq: TRXB), a clinical-stage biotechnology company focused on tissue Treg biology for the discovery and development of immunoregulatory medicines, today reported its financial results for the third quarter ended September 30, 2026, alongside recent business highlights.

The company highlighted positive Phase 1a results for its lead product candidate TRB-061, supporting proof of mechanism, with topline Phase 1b data in atopic dermatitis anticipated in mid-2027. Additionally, TRexBio completed a $133.5 million initial public offering in October 2026, extending its expected cash runway into the second half of 2029.

    Key Highlights

  • Reported positive Phase 1a topline results for TRB-061, demonstrating reproducible activation and expansion of immunoregulatory Tregs in healthy volunteers.
  • TRB-071 is advancing through IND-enabling studies, with a Phase 1 clinical trial expected to initiate in the first half of 2027.
  • Eli Lilly intends to advance partnered program TRB-051 into a Phase 2a clinical trial in lupus with cutaneous involvement.

    Financial Highlights

  • Cash, cash equivalents, and marketable securities totaled $78.2 million as of September 30, 2026, excluding approximately $119.0 million in net proceeds from the October 2026 IPO.
  • Research and development (R&D) expenses were $11.4 million for the third quarter of 2026, compared to $7.0 million for the same period in 2025.
  • General and administrative (G&A) expenses were $2.5 million for the third quarter of 2026, compared to $1.7 million for the third quarter of 2025.
  • Net loss was $13.2 million for the third quarter of 2026, compared to $7.9 million for the third quarter of 2025.

About TRex Bio, Inc.

We are a clinical-stage biopharmaceutical company focused on tissue Treg biology for the discovery and development of immunoregulatory medicines designed to restore immune balance and promote tissue repair to address unmet needs of patients with autoimmune and inflammatory diseases. TRexBio was built on a pivotal scientific insight: that regulatory T cells (“Tregs”) in human tissue are not merely passive suppressors of inflammation, but active orchestrators of tissue immune homeostasis and repair.  Leveraging our Deep Biology drug discovery and design platform, we integrate tissue-level insights into human biology and Treg function to identify and characterize novel targets and approaches for therapeutic intervention.  Our tissue-first conviction and unique insights in Treg biology are the foundation of our pipeline of therapeutic candidates aimed at restoring immune balance and promoting tissue repair for more durable disease control.

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